nüm application video

Application guidelines


Swab the treatment area with antiseptic per facility protocol.


Twist to break tamper evident label and pull off base cap.


Pull off sterile barrier tab on nozzle.


From 3-6 inches away spray the treatment area for 4-6 seconds until the skin just turns white.


Immediately perform procedure.
Numbing effect can last for up to 1 minute.

Vapocoolant studies

A meta-analysis of randomized controlled trials with vapocoolants

Zhu Y, et al. | Read full study

This meta-analysis (11 randomized controlled trials with 1410 patients) suggests that vapocoolant spray significantly decreased pain during intravenous cannulation when compared with placebo spray or no treatment in both adults and children.

Comparing vapocoolant spray vs placebo spray during venipuncture

Mace, SE et al. Department of Emergency Medicine, Cleveland Clinic | Read full study

The median pain of venipuncture was 3 in the placebo group and 1 in the vapocoolant group, P < .001.